ColorectAlert™, FOBT, CEA and Colonoscopy

This 669-patient study compared ColorectAlert™ with fecal occult blood test (FOBT) and carcinoembryonic antigen (CEA) in screening for cancerous and pre-cancerous conditions, using colonoscopy to determine the actual presence of disease in each patient.

ColorectAlert™ demonstrated the best overall level of accuracy of the three tests. For the entire study population, all three tests detected 81 per cent of the cancers (sensitivity), but ColorectAlert™ was much more specific, which means it produced significantly fewer false positive results than either FOBT or CEA. ColorectAlert™ was even more sensitive than FOBT and CEA for early stage (A and B) cancers, and for cancers in asymptomatic patients.

View Abstract - ColorectAlert™: A Novel Test for Colorectal Cancer Screening

View Abstract - Comparison of ColorectAlert™ to FOBT and CEA for Colorectal                      Cancer Screening